NCT01315470

Use of Granulocyte Colony-stimulating Factor for the Treatment of Recurrent Implantation Failure in IVF Patients

Phase 1 Study of the Use of Granulocyte Colony-stimulating Factor for the Treatment of Repeated Implantation Failure in IVF Patients

• Status: Unknown
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: Hadassah Medical Organization · Academic / Other
• Sex: Female
• Age: 20 Years – 45 Years
• Healthy volunteers: Accepted

Summary

The investigators use granulocyte colony-stimulating factor (GCSF) for the treatment of recurrent implantation failure in IVF patient with cause unknown or due to thin endometrium. Several studies showed that GCSF improves embryo development and implantation and increase pregnancy rate.

Detailed description

The investigators use granulocyte colony-stimulating factor (GCSF) for the treatment of repeated implantation failure (5 cycles) in IVF patient with cause unknown or due to thin endometrium. we intend to treat with GCSF during the IVF cycle if thin endometrium (\<6 mm) is the cause for the treatment failure, and during the implantation window if cause unknown.

Conditions

• Infertility

Interventions

Type	Name	Description
DRUG	neupogen administration for women with recurrent IVF failure	neupogen 300 mcg - twice

Timeline

• Start date: 2011-06-01
• Primary completion: 2013-01-01
• Completion: 2013-03-01
• First posted: 2011-03-15
• Last updated: 2011-03-24

Locations

2 sites across 1 country: Israel