NCT01314989

Cyproheptadine as an Appetite Stimulant

Effect of Cyproheptadine on Weight Gain and Feeding Behavior in 2 to 4 Years Old Children With Failure to Thrive

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: St. Justine's Hospital · Academic / Other
• Sex: All
• Age: 2 Years – 4 Years
• Healthy volunteers: Not accepted

Summary

Cyproheptadine is currently clinically used as an appetite stimulant for children with failure to thrive without underlying organic disease. Otherwise, no randomised control trial demonstrates the efficacy of Cyproheptadine on those patients. This is precisely what the investigators intend to demonstrate on this randomised placebo control cross-over trial. Our hypothesis is that Cyproheptadine is more efficient than placebo to improve weight gain and feeding behaviour on 2 to 4 years old children with failure to thrive.

Conditions

• Failure to Thrive

Interventions

Type	Name	Description
DRUG	Cyproheptadine	0,25mg/kg/day orally in 2 doses per day (2mg/5 ml)for 1 month
DRUG	Sugar pill	liquid placebo

Timeline

• Start date: 2010-12-01
• Primary completion: 2011-03-01
• Completion: 2012-01-01
• First posted: 2011-03-15
• Last updated: 2011-03-15

Locations

1 site across 1 country: Canada