NCT01314040

Study to Identify Biomarkers for Protein Intake

Study to Identify Biomarkers for Protein Intake; a Randomized, Fully Controlled Feeding Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 25 (estimated)
• Sponsor: Wageningen University · Academic / Other
• Sex: All
• Age: 18 Years – 40 Years
• Healthy volunteers: Accepted

Summary

Results from observational studies suggest a small beneficial association between protein and blood pressure that may be mainly attributable to the intake of protein from plant sources. In epidemiological studies biomarkers of dietary intake are useful to estimate intake more reliably. Dietary studies using biomarkers of protein intake generally show stronger associations with health outcomes. However, data on biomarkers for specific types of protein (e.g. from dairy, meat, grain and legumes) are scarce. Therefore the purpose of this study is to identify new biomarkers for the intake of protein from meat, dairy and grain. In addition the secondary purpose is to investigate whether intake of protein from these sources influences kidney filtration rate and urinary acid excretion differentially.

Conditions

• Identify New Biomarkers in Blood or Urine After Consumption of Meat Protein, Dairy Protein and Grain Protein in Healthy Subjects.

Interventions

Type	Name	Description
OTHER	Run in diet	Fully controlled dietary period during 9 days. Participants will receive approximately 15 en% of protein. The amount of protein intake from dairy, meat, and grain will be equal to each other
OTHER	High meat protein diet	Fully controlled diet during 7 days. Participants will consume 18 en% protein, mainly from meat.
OTHER	High dairy protein diet	Fully controlled dietary intervention during 7 days. Participants will consume 20 en% protein. Mainly from dairy
OTHER	High grain protein diet	Fully controlled dietary intervention for 7 days. Participants will consume 20 en% of protein. Mainly from grain

Timeline

• Start date: 2011-03-01
• Primary completion: 2011-04-01
• Completion: 2011-04-01
• First posted: 2011-03-14
• Last updated: 2011-06-01

Locations

1 site across 1 country: Netherlands