NCT01312298

General vs. Intrathecal Anesthesia for Total Knee Arthroplasty

General vs. Intrathecal Anesthesia Fort Total Knee Arthroplasty; a Randomized Clinical Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 120 (actual)
• Sponsor: Region Skane · Academic / Other
• Sex: All
• Age: 45 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

Hypothesis: General anesthesia as compared to intrathecal (i.e. spinal anesthesia) anesthesia will result in shorter length of hospital stay for patients undergoing total knee arthroplasty. Primary endpoint: time from end of surgery until the patient is "street ready" Secondary endpoints: will general anesthesia produce less postoperative pain as compared to intrathecal anesthesia? Is there any difference in post operative "dizziness" between the groups.

Detailed description

Hypothesis: General anaesthesia compared to intrathecal anaesthesia will give shorter length of hospital stay (LOS) for patients undergoing total knee arthroplasty (TKA). Primary endpoint: time from end of surgery until the patient meets the discharge criteria. Secondary endpoints: 1. Will general anesthesia produce less post operative pain? 2. Is there any difference in post operative orthostatic function (dizziness) between the groups? 3. Time until the patient meets the discharge criteria from PACU 4. How many patients will need at least one urinary bladder catheterization?

Conditions

• Arthritis

Interventions

Type	Name	Description
PROCEDURE	General anesthesia	Patients will receive general anesthesia using propofol 10 mg/ml and remifentanil 50 ug/ml
PROCEDURE	Regional anesthesia	Patients will receive intrathecal anesthesia

Timeline

• Start date: 2011-08-01
• Primary completion: 2012-06-01
• Completion: 2013-01-01
• First posted: 2011-03-10
• Last updated: 2013-03-07

Locations

1 site across 1 country: Sweden