NCT01310699

Study of Flat Polyp Detection Using New Narrow Band Imaging (NBI) Compared to White Light Colonoscopy - The FIND FLAT Colonoscopy Study

Full Inspection With Narrow Band Imaging (NBI) for Detection of Flat Lesions And Tumors During Colonoscopy- The FIND FLAT Colonoscopy Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 281 (actual)
• Sponsor: VA Palo Alto Health Care System · Federal
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

We hypothesize that high definition narrow band imaging (NBI) colonoscopy compared to high definition white light colonoscopy will detect an increased number of nonpolypoid (flat and depressed) colorectal neoplasm.

Detailed description

Interval colorectal cancers diagnosed within a three year period following a clearing colonoscopy have been reported at a rate of 1 cancer/1000 person years.The majority of these cancers are likely a consequence of a missed neoplastic lesion during routine colonoscopy. Recent tandem colonoscopy studies have shown no significant difference in adenoma miss or detection rates using narrow band imaging as compared to colonoscopy using white light. However, higher detection of flat neoplastic lesions using NBI was shown in a meta-analysis and should be furthered studied, especially considering that they are thought to be a strong contributor to a false negative colonoscopy.

Conditions

• Colorectal Neoplasms
• Colonic Polyps
• Colorectal Cancer

Interventions

Type	Name	Description
DEVICE	Olympus Colonoscope CFHQ190AL	Technically improved colonoscope with close focus high definition narrow band imaging.

Timeline

• Start date: 2013-01-01
• Primary completion: 2016-05-01
• Completion: 2016-08-01
• First posted: 2011-03-08
• Last updated: 2017-12-06
• Results posted: 2017-04-06

Locations

3 sites across 1 country: United States