Trials / Completed
CompletedNCT01309061
The Effect of Human Adipose Tissue-derived MSCs in Romberg's Disease
Preliminary Investigation of the Effect of Human Adipose Tissue-derived Mesenchymal Stem Cell in Progressive Hemifacial Atrophy(Romberg's Disease)
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 5 (actual)
- Sponsor
- R-Bio · Industry
- Sex
- All
- Age
- 18 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to investigate the efficacy and safety of autologous transplantation of adipose tissue derived mesenchymal stem cells (MSCs) in patient with progressive hemifacial atrophy.
Detailed description
Adipose derived mesenchymal stem cells (AdMSCs) represent an attractive and ethical cell source for stem cell therapy. With the recent demonstration of MSC homing properties, intramuscular aplications of MSCs to cell-damaged diseases have increased. In a human clinical trial, five patients who had suffered a progressive hemifacial atrophy( Romberg's disease) were intramuscular administered autologous hAdMSCs (1×10e7 cells/500ul) with autologous microlipoinjection one time.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Autologous Adipose Tissue derived MSCs Transplantation | Intramuscular infusion of Autologous Adipose Tissue derived MSCs with autologous microlipoinjection. Dose: 1x10e7 cells/500ul/lipoinjection 20ml |
Timeline
- Start date
- 2008-03-01
- Primary completion
- 2009-12-01
- Completion
- 2010-02-01
- First posted
- 2011-03-04
- Last updated
- 2019-06-05
Locations
1 site across 1 country: South Korea
Source: ClinicalTrials.gov record NCT01309061. Inclusion in this directory is not an endorsement.