Clinical Trials Directory

Trials / Completed

CompletedNCT01307033

A Long-term Study of the Safety of MK-0954A in Patients With Essential Hypertension (MK-0954A-351)

A Phase III, Randomized, Active-comparator Controlled and a Long-term Clinical Trial to Study the Safety of MK-0954A (L100/H12.5 mg) in Japanese Patients With Essential Hypertension Uncontrolled With MK-954H (L50/H12.5 mg) [PREMINENT®]

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
278 (actual)
Sponsor
Organon and Co · Industry
Sex
All
Age
20 Years – 80 Years
Healthy volunteers
Not accepted

Summary

This study is being conducted to evaluate the safety of MK-0954A (L100/H12.5 mg) in essential hypertension participants who are uncontrolled with MK-954H (L50/H12.5 mg).

Conditions

Interventions

TypeNameDescription
DRUGMK-0954ATablet containing losartan potassium (100 mg) and hydrochlorothiazide (12.5 mg), once daily
DRUGMK-954HTablet containing losartan potassium (50 mg) and hydrochlorothiazide (12.5 mg), once daily
DRUGPlacebo to MK-0954APlacebo tablet to match MK-0954A, once daily
DRUGPlacebo to MK-954HPlacebo tablet to match MK-954H, once daily

Timeline

Start date
2011-03-29
Primary completion
2012-12-04
Completion
2012-12-04
First posted
2011-03-02
Last updated
2024-05-17
Results posted
2014-01-06

Source: ClinicalTrials.gov record NCT01307033. Inclusion in this directory is not an endorsement.