Clinical Trials Directory

Trials / Completed

CompletedNCT01303952

Therapy of Chronic Cold Agglutinin Disease With Eculizumab

Therapy for Chronic Cold Agglutinin Disease: A Prospective, Non-Randomized Multi-Center Study Demonstrating the Efficacy of Terminal Complement Inhibition in Patients With Cold Agglutinin Disease Using Eculizumab

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
13 (actual)
Sponsor
University Hospital, Essen · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Evaluation of the efficacy and safety of eculizumab in symptomatic or transfusion-dependent patients with untreated or refractory hemolytic cold agglutinin disease(CAD)

Conditions

Interventions

TypeNameDescription
DRUGEculizumabWeekly treatment with eculizumab (600 mg) via IV infusion for 4 doses followed the next week by eculizumab (900 mg) IV infusion and maintenance treatment with Eculizumab (900 mg) via IV infusion every other week for 21 weeks

Timeline

Start date
2011-01-01
Primary completion
2014-09-01
Completion
2015-06-01
First posted
2011-02-25
Last updated
2017-07-19

Locations

1 site across 1 country: Germany

Source: ClinicalTrials.gov record NCT01303952. Inclusion in this directory is not an endorsement.