Clinical Trials Directory

Trials / Completed

CompletedNCT01302171

Bone Marrow Derived Adult Stem Cells for Dilated Cardiomyopathy

Randomised Controlled Trial to Compare the Effects of G-CSF (Granocyte™) and Autologous Bone Marrow Progenitor Cells on Quality of Life and Left Ventricular Function in Patients With Idiopathic Dilated Cardiomyopathy

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
60 (actual)
Sponsor
Barts & The London NHS Trust · Academic / Other
Sex
All
Age
18 Years – 80 Years
Healthy volunteers
Not accepted

Summary

A randomised, double-blind, placebo-controlled trial to evaluate the role of intracoronary injection of progenitor cells compared to placebo injection in patients with Dilated Cardiomyopathy who have been pre-treated with G-CSF (Granocyte™) injections for 5 days, and patients treated with a 5 day course of G-CSF (Granocyte™) injection only compared to placebo injection

Conditions

Interventions

TypeNameDescription
DRUGgranulocyte colony stimulating factor (GCSF)10mcg/kg per day 5 days
PROCEDUREbone marrow mononuclear cellsintra coronary injection of stem cells or placebo

Timeline

Start date
2010-08-01
Primary completion
2012-12-01
Completion
2013-07-01
First posted
2011-02-24
Last updated
2013-11-15

Locations

1 site across 1 country: United Kingdom

Source: ClinicalTrials.gov record NCT01302171. Inclusion in this directory is not an endorsement.