NCT01301131

Probiotics for Prevention of Ventilator-Associated Pneumonia (VAP)

Randomized Controlled Trial of Fermented Dairy Product Containing L. Casei Shirota for Prevention of Ventilator-Associated Pneumonia

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 150 (estimated)
• Sponsor: Mahidol University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Hospitalized patients with ventilator are randomized to receive fermented dairy product containing L. casei shirota or nothing. The main outcome is development of ventilator-associated pneumonia (VAP)

Detailed description

Fermented dairy product containing L. casei shirota has bee shown to inhibit multi-drug-resistant bacteria. This study is conducted to determine if Fermented dairy product containing L. casei shirota can prevent ventilator-associated pneumonia.

Conditions

• Drug Safety

Interventions

Type	Name	Description
OTHER	Probiotics	80 ml of fermented dairy product containing L. casei shirota via nasogastric tube once daily and 80 ml of fermented dairy product containing L. casei shirota oral rinse once daily
OTHER	control	usual oral care

Timeline

• Start date: 2011-12-01
• Primary completion: 2013-08-01
• Completion: 2013-10-01
• First posted: 2011-02-23
• Last updated: 2012-01-02

Locations

1 site across 1 country: Thailand