NCT01295242

Natural History of Human Papillomavirus (HPV) Infections in Mid-Adult Women (WHIM)

Natural History of HPV Infections in Mid-Adult Women

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 409 (actual)
• Sponsor: University of Washington · Academic / Other
• Sex: Female
• Age: 30 Years – 50 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to determine rates of oral and genital human papillomavirus (HPV) infections, and look at risk factors for HPV infection in healthy mid-adult women.

Detailed description

The investigators propose a longitudinal study of 500 women in order to determine rates and risk factors for HPV infections in 30-50 year old women. Participants will be followed for 6 months and will be asked to complete online questionnaires on their health, sexual behavior, HPV vaccinations, and cervical cancer screening. The investigators will ask participants to self-collect monthly vaginal swab samples and self-collect 2 oral swab samples. Women will also be asked to provide 2 blood samples. All swab samples will be tested for type-specific HPV deoxyribonucleic acid (DNA) using a polymerase chain reaction (PCR)-based assay, blood samples will be tested for HPV antibodies.

Conditions

• Papillomavirus Infections

Timeline

• Start date: 2011-02-01
• Primary completion: 2012-08-01
• Completion: 2012-08-01
• First posted: 2011-02-14
• Last updated: 2013-11-19

Locations

1 site across 1 country: United States