NCT01292395

Effects of Dietary Protein on Musculoskeletal Health During Calorie Deficiency

The Musculoskeletal Response to Energy Deficit: Defining Optimal Protein Intake

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 42 (actual)
• Sponsor: United States Army Research Institute of Environmental Medicine · Federal
• Sex: All
• Age: 18 Years – 42 Years
• Healthy volunteers: Accepted

Summary

Military personnel face many physiological challenges, including sustained physical activity and prolonged periods of negative energy balance. Chronic energy deficiency often results in a loss of skeletal muscle mass and can reduce overall bone health. Recent evidence suggests that dietary interventions that provide protein in excess of the current national dietary recommendation may confer protection against the negative effects of energy deficiency on the musculoskeletal system. The primary objective of this randomized, controlled study is to assess the effects dietary protein intake spanning the current acceptable macronutrient distribution range on musculoskeletal health following prolonged energy deficiency. Findings from this investigation will improve current understanding of dietary conditions necessary to reduce the damaging effects of caloric deficiency on musculoskeletal health in warfighters. Furthermore, given the rise in obesity in military populations, findings may aid in the development of nutritional weight management strategies that promote healthy weight loss without compromising musculoskeletal health.

Conditions

• Weight Loss
• Muscle Loss
• Bone Loss

Interventions

Type	Name	Description
OTHER	Dietary Protein Intake	Protein intakes within the current recommendation

Timeline

• Start date: 2010-09-01
• Primary completion: 2011-11-01
• Completion: 2011-11-01
• First posted: 2011-02-09
• Last updated: 2017-08-14

Locations

1 site across 1 country: United States