NCT01292343

Triclosan Toothpaste and Third Molar Surgery

Effect of a Triclosan Containing Dentifrice on Oral Bacteria and Postoperative Complications Following Third Molar Surgery

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 141 (actual)
• Sponsor: University of Rochester · Academic / Other
• Sex: All
• Age: 18 Years – 35 Years
• Healthy volunteers: Accepted

Summary

Triclosan containing dentifrices are effective in the prevention of inflammatory complications following third molar surgery through reducing preoperative oral bacteria load.

Detailed description

This study may provide evidence on the effect of triclosan containing dentifrice on oral bacteria and oral inflammation prior to third molar surgery, and on the incidence of inflammatory complications after the surgery. If proven effective, dentifrice containing triclosan may be recommended prior to tooth extractions and replace antibiotics and other antimicrobial products as a prophylactic procedure before oral surgery procedures.

Conditions

• Dry Socket
• Wound Infection

Interventions

Type	Name	Description
OTHER	Colgate Total Toothpaste	Toothbrushing with Colgate Total Toothpaste
OTHER	Colgate Regular Toothpaste	Toothbrushing with Colgate regular toothpaste

Timeline

• Start date: 2008-02-01
• Primary completion: 2013-02-01
• Completion: 2013-02-01
• First posted: 2011-02-09
• Last updated: 2015-10-28

Locations

1 site across 1 country: United States