NCT01291576

Functional Outcomes of Surgical Management of Deep Endometriosis Infiltrating the Rectum

Randomized Trial Comparing Digestive and Urinary Dysfunction Secondary to 2 Surgical Techniques Used in the Management of Deep Endometriosis Infiltrating the Rectum: Colorectal Resection and Rectal Nodules Excision (ENDORE)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: University Hospital, Rouen · Academic / Other
• Sex: Female
• Age: 18 Years – 45 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether performing colorectal resection in deep endometriosis infiltrating the rectum is responsible for a higher rate of postoperative digestive and urinary dysfunction when compared to rectal nodules excision (conservation of the rectum).

Detailed description

The study compare digestive and urinary functional outcomes following surgical management of rectal endometriosis by either colorectal resection or conservative surgery (shaving or full thickness excision of rectal nodules). Patients managed for rectal endometriosis are randomized in two arms, and followed up for 24 months. The assessment of digestive and urinary functions is performed at 6, 12, 18 and 24 months using standardized questionnaires. Postoperative complications and improvement of endometriosis related pain are also recorded.

Conditions

• Endometriosis, Rectum

Interventions

Type	Name	Description
PROCEDURE	Rectal/colorectal segmental resection	Resection of the rectum +/- sigmoid colon involved by the deep infiltrating endometriosis
PROCEDURE	Rectal nodule excision	Either full thickness excision or rectal shaving

Timeline

• Start date: 2011-03-01
• Primary completion: 2013-09-01
• Completion: 2015-09-22
• First posted: 2011-02-08
• Last updated: 2025-10-06

Locations

3 sites across 1 country: France