Clinical Trials Directory

Trials / Completed

CompletedNCT01290445

Varenicline Pregnancy Cohort Study

Varenicline Pregnancy Cohort Study Protocol Chantix(Registered)/Champix(Registered) (Varenicline Tartrate)

Status
Completed
Phase
Study type
Observational
Enrollment
885,185 (actual)
Sponsor
Pfizer · Industry
Sex
All
Age
Healthy volunteers
Not accepted

Summary

A prospective population-based cohort study to examine whether varenicline use during pregnancy is associated with an increased risk of major congenital malformations in infants above that associated with smoking during pregnancy.

Detailed description

Sampling will not be employed. The data sources record nearly all (\>98.6%) births in Denmark and Sweden.

Conditions

Interventions

TypeNameDescription
DRUGvareniclineThis is a non-interventional study. Exposure in utero to varenicline is observed, not assigned.
BEHAVIORALcigarette smoke from maternal smokingThis is a non-interventional study. Exposure in utero to cigarette smoke from maternal smoking is observed, not assigned.
OTHERNon-ExposureThis is a non-interventional study. Non-exposure in utero to varenicline and cigarette smoke from maternal smoking is observed, not assigned.

Timeline

Start date
2007-09-13
Primary completion
2016-05-01
Completion
2016-05-01
First posted
2011-02-07
Last updated
2023-07-24
Results posted
2019-01-22

Source: ClinicalTrials.gov record NCT01290445. Inclusion in this directory is not an endorsement.