Trials / Completed
CompletedNCT01289756
Influence of Pharmacogenetic Factors, Paroxetine and Clarithromycin on Pharmacokinetics of Clomiphene
- Status
- Completed
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 20 (actual)
- Sponsor
- Robert Bosch Gesellschaft für Medizinische Forschung mbH (RBMF) · Academic / Other
- Sex
- Female
- Age
- 18 Years – 45 Years
- Healthy volunteers
- Accepted
Summary
Aim of the study is the clinical validation of the metabolism and the pharmakokinetic of Clomifen in correlation to CYP2D6 and inhibition of CYP3A4.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Clomiphene | clomiphene once 100 mg oral |
| DRUG | clomiphene and paroxetine | clomiphene 100mg and paroxetine 3x40mg |
| DRUG | clomiphene and clarithromycin | clomiphene 100mg and clarithromycin 9x500mg |
Timeline
- Start date
- 2009-12-01
- Primary completion
- 2014-11-01
- Completion
- 2014-11-01
- First posted
- 2011-02-04
- Last updated
- 2015-02-24
Locations
1 site across 1 country: Germany
Source: ClinicalTrials.gov record NCT01289756. Inclusion in this directory is not an endorsement.