Clinical Trials Directory

Trials / Completed

CompletedNCT01287689

Assessment of Immunoglobulins (IgG) in a Long-term Non-interventional Study

An Open, Uncontrolled, Non-interventional Observational Cohort Outcome Study of Immunoglobulins in 3 Indications: Primary and Secondary Immunodeficiencies and Neurological Auto-immune Diseases

Status
Completed
Phase
Study type
Observational
Enrollment
685 (actual)
Sponsor
Technische Universität Dresden · Academic / Other
Sex
All
Age
Healthy volunteers
Not accepted

Summary

This non-interventional, epidemiological study assesses long-term outcomes in subjects receiving immunoglobulins (IgG) for any treatment purpose, irrespective of the regimen prescribed by the treating physician, under routine clinical conditions in Germany. Long-term outcome data are collected on patient characteristics in the various indications, drug utilization of intravenous and subcutaneous IgG (e.g. treatment and dosing patterns), effectiveness (i.e. number of infections), tolerability, health related quality of life, and economic variables (number of hospitalizations, sick-leave days etc.) with the possibility to estimate direct costs.

Detailed description

In view of the broad range of indications in immunodeficiency and immunomodulation, it is of interest to document the use of IgG under the conditions of everyday practice and to analyze the endpoints (outcomes). A prospective cohort study such as this is an important evidence source for such rare diseases as those mentioned above. The aim of this outcome study is to fill the gap of the lack of long-term data in these rare diseases treated with IgG.

Conditions

Interventions

TypeNameDescription
OTHERImmunoglobulin G (IgG)Not applicable. All interventions are at the discretion of the investigator. All marketed IgG formulations can be documented.

Timeline

Start date
2010-07-01
Primary completion
2016-12-31
Completion
2016-12-31
First posted
2011-02-01
Last updated
2017-08-01

Locations

7 sites across 1 country: Germany

Source: ClinicalTrials.gov record NCT01287689. Inclusion in this directory is not an endorsement.