NCT01287403

Response of Alkylresorcinols to Different Cereals

Response of Alkylresorcinols and Other Biomarkers to Different Cereals

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 14 (actual)
• Sponsor: Société des Produits Nestlé (SPN) · Industry
• Sex: All
• Age: 18 Years – 55 Years
• Healthy volunteers: Accepted

Summary

Cereal grains contain a wide variety of different phytochemicals which may play different roles in physiology. Their response in plasma and urine after a meal is poorly defined for most cereals. This study will investigate the plasma response and urinary excretion of cereal compounds after eating 6 different types of cereal preparation, with a focus on alkylresorcinols.

Detailed description

This was a cross-over, randomized, double blind study with 6 arms (flours of different composition). Thirteen subjects completed the trial, where 100 g of each flour, mixed with 300 mL milk, was fed to all subjects.

Conditions

• Healthy

Interventions

Type	Name	Description
OTHER	Refined wheat flour	A treated cereal flour mixed with milk.
OTHER	Esterase wholegrain wheat flour	A treated cereal flour mixed with milk.
OTHER	Wholegrain wheat flour	A treated cereal flour mixed with milk.
OTHER	Liquid whole grain wheat flour	A treated cereal flour mixed with milk.
OTHER	Wholegrain barley flour	A treated cereal flour mixed with milk.
OTHER	Liquid wholegrain barley flour	A treated cereal flour mixed with milk.

Timeline

• Start date: 2011-01-01
• Primary completion: 2012-08-01
• Completion: 2012-12-01
• First posted: 2011-02-01
• Last updated: 2018-08-31
• Results posted: 2013-08-14

Locations

1 site across 1 country: Switzerland