NCT01284829

Performance of 18F-Fluorodeoxyglucose Positron Emission Tomography (FDG-PET) in the Diagnosis of Indeterminate Adrenal Tumors on Conventional Imaging: A French Prospective Multicentric Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 87 (actual)
• Sponsor: Assistance Publique Hopitaux De Marseille · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This is a prospective study which aims to validate a new diagnostic approach in the tissue characterization of adrenal tumors indeterminate on conventional imaging. For this purpose, it is not necessary to have a control group since the diagnostic accuracy in a well defined subset of patients. Visit 0 : Enrollment, eligibility. Visit 1 : FDG-PET. Visit 2 : Postoperative visit. Visit 3 : 6 months post-PET. Visit 4 : 12 months post-PET.

Detailed description

Primary objective The primary objective is to assess the diagnostic accuracy of FDG-PET, particularly the SUVmax tumor/liver ratio, in the diagnosis of indeterminate adrenal tumors on conventional imaging. Secondary objectives * To assess the diagnostic accuracy of the tumor SUVmax, and SUVmax of the tumor/mean SUV of the liver. * To evaluate the relationship between SUVmax tumor/liver ratio and Weiss score. * To evaluate the impact of the use of FDG-PET on the treatment options. * To evaluate the economic impact of FDG-PET in the management of indeterminate adrenal tumors (ancillary study).

Conditions

• Adrenal Tumors

Interventions

Type	Name	Description
OTHER	FDG-PET scan

Timeline

• Start date: 2011-02-04
• Primary completion: 2013-10-10
• Completion: 2023-04-05
• First posted: 2011-01-27
• Last updated: 2023-04-06

Locations

1 site across 1 country: France