NCT01283672

Acute Heart Health Benefits of Whole Grain Barley and Oats in Healthy Men and Women

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 18 (estimated)
• Sponsor: United States Department of Agriculture (USDA) · Federal
• Sex: All
• Age: 25 Years – 70 Years
• Healthy volunteers: Accepted

Summary

The objectives of this study are the following: 1) to determine the acute effect of whole grain barley on risk factors of cardiovascular disease compared to a diet low in whole grain, and 2) to compare the effects of whole grain barley to those of whole grain oats to determine if the response to these two grains is similar.

Detailed description

Whole grains contain bioactive components that may contribute to reduced risk of cardiovascular disease, and there may be significant differences among whole grain sources with respect to ability to alter biomarkers of cardiovascular disease. This acute study is designed to determine if whole grain barley improves postprandial lipid metabolism and improves endothelial function. Further, we will determine if acute consumption of whole grain barley versus acute consumption of whole grain oats results in differential response with respect to biomarkers of cardiovascular disease risk.

Conditions

• Cardiovascular Disease

Interventions

Type	Name	Description
OTHER	Controlled diet with whole grain barley, whole grain oats, or low grain diet	Participants will consume a standardized diet for 3 days prior to the treatment intervention meal. Meals will be prepared using traditional American foods with a macronutrient composition representative of a typical American diet. Participants will be instructed to eat all foods and only foods provided to them, with the exception of water, coffee, tea, and diet soda.

Timeline

• Start date: 2011-01-01
• Primary completion: 2011-04-01
• Completion: 2011-04-01
• First posted: 2011-01-26
• Last updated: 2011-07-18

Locations

1 site across 1 country: United States