Clinical Trials Directory

Trials / Completed

CompletedNCT01279954

Abatacept in the Treatment of Uveitis

An Openlabel, Phase II Trial of Abatacept (Orencia) in the Treatment of Refractory Non-infectious Uveitis.

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
10 (actual)
Sponsor
Oregon Health and Science University · Academic / Other
Sex
All
Age
6 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to assess the safety and efficacy of abatacept in the treatment of uveitis.

Conditions

Interventions

TypeNameDescription
DRUGAbataceptSubjects will receive approximately 10 mg/kg rounded to the nearest 25 mg for the first 6 months of the trial. At 6 months subjects will then be randomized to receive either 5 mg/kg or 10 mg/kg. Abatacept will be administered as a 30-minute intravenous infusion. Following the initial administration, abatacept will be given at 2 and 4 weeks after the first infusion and every 4 weeks thereafter for up to 2 years.

Timeline

Start date
2012-01-01
Primary completion
2017-06-01
Completion
2017-06-01
First posted
2011-01-20
Last updated
2019-02-21
Results posted
2019-02-21

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT01279954. Inclusion in this directory is not an endorsement.