Clinical Trials Directory

Trials / No Longer Available

No Longer AvailableNCT01279798

Expanded Access Multicenter Study of Lucanix® (Belagenpumatucel-L)

Expanded Access Multicenter Study of Lucanix® (Belagenpumatucel-L) in Advanced Non-small Cell Lung Cancer.

Status
No Longer Available
Phase
Study type
Expanded Access
Enrollment
Sponsor
NovaRx Corporation · Industry
Sex
All
Age
18 Years
Healthy volunteers

Summary

This is an expanded access protocol designed to make Lucanix® available to subjects with advanced non-small cell lung cancer (NSCLC) who are not eligible for the Phase III Protocol, NR001-03. A total of 45 patients will be enrolled into the study.

Detailed description

The primary objective of this study is to increase the overall survival of the study subjects by providing expanded access to Lucanix. Overall survival and progression-free survivals will be compared with historical controls. The secondary objectives of this study are: * Evaluate the best overall tumor response. * Evaluate progression-free survival (PFS). * Evaluate treatment toxicity.

Conditions

Interventions

TypeNameDescription
BIOLOGICALLucanix® (belagenpumatucel-L)Subjects will receive up to 12 monthly (28-35 day interval) Lucanix injections at a dose of 2.5 × 10e7 cells per injection.

Timeline

First posted
2011-01-19
Last updated
2011-03-01

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT01279798. Inclusion in this directory is not an endorsement.