NCT01279655

Motor Training and White Matter in Multiple Sclerosis (MS)

The Influence of a tDCS Combined Long-term Motor Training Program on Structural White Matter Changes in the Brain, Functionality and Psychological Outcome Measures in Multiple Sclerosis.

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Hasselt University · Academic / Other
• Sex: All
• Age: 18 Years – 68 Years
• Healthy volunteers: Accepted

Summary

In the current study the researchers will firstly investigate whether a bimanual coordination training protocol (20 min/day, for 8 consecutive weeks) correlates with changes in white matter architecture and improved upper-limb functionality in patients with multiple sclerosis. Secondly, the researchers predict that motor learning is more efficient when it is combined with anodal transcranial direct current (tDCS) stimulation on the left primary motor cortex.

Conditions

• Multiple Sclerosis

Interventions

Type	Name	Description
DEVICE	tDCS	20 min, 1mA, 8 weeks (5 days a week, 20 min a day)
BEHAVIORAL	Bimanual Training	The training program consisted of a bimanual etch-a-sketch task. By rotating two wheels subjects have to match a line presented on the screen with the cursor. 8 weeks (5 days a week, 20 min a day)

Timeline

• Start date: 2011-01-01
• Primary completion: 2011-12-01
• Completion: 2013-05-01
• First posted: 2011-01-19
• Last updated: 2012-09-12

Locations

1 site across 1 country: Belgium