NCT01278238

Optimization of Hemodynamic Conditions During Caesarean Section Under Spinal Anaesthesia

Hemodynamic Effect of Prophylactic Phenylephrine Versus Lower Limb Compression in Women During Caesarean Section Under Spinal Anaesthesia

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 120 (actual)
• Sponsor: Anestesiavdelingen Baerum Sykehus · Academic / Other
• Sex: Female
• Age: 18 Years – 40 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to determine wether intravenous Phenylephrine, administered as start bolus and following continuous infusion (specific dosage per weight), or optimal lower limb bandaging is more effective in preventing hypotension during caesarean section under spinal anaesthesia in healthy women. The hypothesis is that the Phenylephrine model is superior to lower limb compression in preventing hypotension.

Conditions

• Caesarean Section

Interventions

Type	Name	Description
DRUG	Phenylephrine	Intravenous infusion Dosage 0,25 microgram/kg bodyweight as bolus, continuous infusion with 0,25 microgram/kg/min
DEVICE	Lower limb compression	Tight bandaging of lower extremity up to hips with compression bandages
OTHER	Placebo	Neither phenylephrine nor lower limb bandaging

Timeline

• Start date: 2010-01-01
• Primary completion: 2012-10-01
• Completion: 2012-10-01
• First posted: 2011-01-17
• Last updated: 2013-01-11

Locations

1 site across 1 country: Norway