NCT01277835

Intravenous Lidocaine Infusion During Video-assisted Thoracic Procedures for Improved Pain Control

Intravenous Lidocaine Infusion During VATS Procedures Reduces Postoperative Analgesic Requirements

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 48 (actual)
• Sponsor: University of Saskatchewan · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether intravenous lidocaine infusion during a video-assisted chest surgery is effective in reducing the pain involved after the surgery. The hypothesis is that continuous lidocaine infusion during video-assisted thoracoscopic surgery (VATS) reduces morphine consumption and postoperative pain.

Detailed description

Despite newer surgical techniques, many patients still experience moderate to severe postoperative pain after minimally invasive surgeries. Thoracoscopic surgeries are often associated with severe postoperative pain. To relieve the pain, potent narcotics have to be used, which have many side effects. Surgical patients would therefore benefit from an intra-operative analgesic regimen that is safe and effective, has minimal side effects and can reduce their postoperative narcotic requirements. Intravenous lidocaine has been shown previously to relieve cancer pain, chronic pain, and pain after other types of surgery.

Conditions

• Pain

Interventions

Type	Name	Description
DRUG	Lidocaine Infusion	Infusion of lidocaine 3mg/min or 2mg/min during surgery
DRUG	Placebo	Saline Infusion at same rate as experimental arm

Timeline

• Start date: 2010-02-01
• Primary completion: 2013-02-01
• Completion: 2013-02-01
• First posted: 2011-01-17
• Last updated: 2014-12-02

Locations

1 site across 1 country: Canada