NCT01276626

Study of Bacteria on Mood and Bowel Symptoms in Patients With Irritable Bowel Syndrome

Pilot Study of Probiotic Bifidobacterium Longum (B. Longum) on Mood and Bowel Symptoms in Patients With Irritable Bowel Syndrome (IBS).

• Status: Completed
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: Société des Produits Nestlé (SPN) · Industry
• Sex: All
• Age: 21 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether probiotic bacterium Bifidobacterium longum (B. longum) can improve mood and bowel symptoms in patients with Irritable bowel syndrome (IBS). The patients will be treated with probiotic or placebo for 6 weeks. Their mood, memory, general well-being and bowel symptoms will be assessed before, at the end of the treatment and 4 weeks later. Brain activation pattern, changes in gut bacteria, metabolic profile and inflammatory markers will be also measured.

Conditions

• Irritable Bowel Syndrome
• IBS

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Bifidobacterium longum	Powder containing Bifidobacterium longum in maltodextrin.
OTHER	Maltodextrin	Powder containing only maltodextrin

Timeline

• Start date: 2011-01-01
• Primary completion: 2014-06-01
• Completion: 2014-06-01
• First posted: 2011-01-13
• Last updated: 2014-08-05

Locations

1 site across 1 country: Canada