Trials / Completed
CompletedNCT01274052
Study of Postprandial Incretin Response in Women With Gestational Diabetes
Reduced Postprandial GLP-1 Response in Gestational Diabetes Mellitus: a Fully Reversible Phenomenon
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 19 (actual)
- Sponsor
- University Hospital, Gentofte, Copenhagen · Academic / Other
- Sex
- Female
- Age
- —
- Healthy volunteers
- Not accepted
Summary
The researchers investigated nineteen pregnant women in third trimester and again postpartum. At the experimental days we performed a mealtest and drew blood for analyses of glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), insulin, C-peptide and glucagon. The researchers aimed to investigate whether women with gestational diabetes mellitus exhibit decreased postprandial GLP-1 responses, and if so, whether this deficiency ceases following delivery when normal glucose tolerance is reestablished.
Detailed description
The researchers investigated nineteen pregnant women in third trimester and again postpartum. At the experimental days we performed a mealtest and drew blood for analyses of glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), insulin, C-peptide and glucagon. The researchers aimed to investigate whether women with gestational diabetes mellitus exhibit decreased postprandial GLP-1 responses, and if so, whether this deficiency ceases following delivery when normal glucose tolerance is reestablished.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Meal test | Liquid meal test |
Timeline
- Start date
- 2007-03-01
- Primary completion
- 2008-07-01
- Completion
- 2008-07-01
- First posted
- 2011-01-11
- Last updated
- 2011-01-11
Locations
1 site across 1 country: Denmark
Source: ClinicalTrials.gov record NCT01274052. Inclusion in this directory is not an endorsement.