NCT01274039

Comparing Eye Pressure Using Maximal Tolerated Local Therapy or Systemic Acetazolamide

Comparing Eye Pressure Using Maximal Tolerated Local Therapy or Systemic Acetazolamide. A Possible Pretreatment for Trabeculectomy Surgery.

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: —
• Sponsor: University of Cologne · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Local therapy for glaucoma is known to induce a conjunctival inflammation. Because of this, trabeculectomy is more likely to fail. The investigators exchange the local therapy by systemic therapy using acetazolamide and measure the eye pressure using local therapy and systemic therapy using acetazolamide. The investigators suspect an elevated eye pressure using acetazolamide compared to local therapy. In summary acetazolamide could be a better choice in reference to conjunctival inflammation, but a worse choice in reference to controlling eye pressure.

Conditions

• Control of Elevated Eye Pressure by Local and Systemic Therapy

Interventions

Type	Name	Description
DRUG	Acetazolamide for glaucoma patients to lower eye pressure	Acetazolamide tablets 3 times daily for 3 to 4 weeks

Timeline

• Start date: 2009-02-01
• Primary completion: 2011-02-01
• Completion: 2012-02-01
• First posted: 2011-01-11
• Last updated: 2013-04-15

Locations

1 site across 1 country: Germany