NCT01271257

Pharmacokinetics of Misoprostol With Titrated Oral Administration

Phase 1 Study of Titrated Oral Misoprostol

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: China Medical University Hospital · Academic / Other
• Sex: Female
• Age: 20 Years – 40 Years
• Healthy volunteers: Accepted

Summary

The AUC240, AUC360, and AUC480 of titrated oral misoprostol are greater than traditional oral misoprostol.

Detailed description

The primary outcomes measures of the study are the area under the curve of serum concentration of misoprostol acid against time up to 240, 360 and 480 minutes.

Conditions

• Hypotonic; Labor

Interventions

Type	Name	Description
DRUG	Misoprostol	20 microgram PO per hour for 8 doses or 80 microgram PO per 4 hours for 2 doses

Timeline

• Start date: 2011-01-01
• Primary completion: 2014-12-01
• Completion: 2014-12-01
• First posted: 2011-01-06
• Last updated: 2016-01-28

Locations

1 site across 1 country: Taiwan