NCT01271088

Protective Effect of N-acetylcysteine Against From Ototoxicity

Phase 3 Study of Protective Effect of N-acetylcysteine Against From Ototoxicity

• Status: Completed
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: TC Erciyes University · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

Peritonitis is currently one of the leading complications of continuous ambulatory peritoneal dialysis (CAPD). Aminoglycosides and vancomycin are used in the treatment of CAPD peritonitis despite their potential risk for ototoxicity. NAC is a molecule used in the treatment and prophylaxis of many diseases related to oxidative stress. The aim of this study was to examine whether ototoxicity due to antibiotics used in the treatment of CAPD peritonitis can be prevented by N-acetylcysteine

Detailed description

NAC, a thiol-containing antioxidant because of this,we want to investigate antioxidant status.

Conditions

• Hearing Loss, Extreme

Interventions

Type	Name	Description
DRUG	N-acetylcysteine	N-acetylcysteine 600 mg twice a day,one week after administration of antibiotics

Timeline

• Start date: 2010-06-01
• Primary completion: 2011-11-01
• Completion: 2011-11-01
• First posted: 2011-01-06
• Last updated: 2011-11-16

Locations

1 site across 1 country: Turkey (Türkiye)