NCT01271062

Restoration of Beta Cell Function and Cardiovascular Parameters in Relation to Adipoinsular and Enteroinsular Axes After Gastric Bypass Surgery

Restoration of Beta Cell Function and Cardiovascular Parameters in Relation to Adipoinsular and Enteroinsular Axes After Gastric Bypass Surgery in Severely Obese Patients With Type 2 Diabetes

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 55 (actual)
• Sponsor: Cantonal Hospital of St. Gallen · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Bariatric operations such as the gastric bypass procedure provide a unique in vivo model of improvement of pathological beta cell function. The presented double-centre study aims to comprehensively investigate different aspects of beta cell function in patients with type 2 diabetes (T2DM) with a wide range of disease duration after gastric bypass. In parallel, our project will address the aspects of changes in enteroinsular and adipoinsular axes as well as the early and late changes of other defined parameters after gastric bypass surgery.

Conditions

• Diabetes Mellitus, Type 2
• Bariatric Surgery Candidate

Interventions

Type	Name	Description
PROCEDURE	gastric bypass surgery
PROCEDURE	abdominal surgery
BEHAVIORAL	very low caloric diet

Timeline

• Start date: 2009-10-01
• Primary completion: 2012-11-01
• Completion: 2012-12-01
• First posted: 2011-01-06
• Last updated: 2013-03-07

Locations

2 sites across 2 countries: Austria, Switzerland