NCT01269151

Ranibizumab Short- and Log-term Effects on Retinal Function in wAMD

A Prospective, Non-randomized, Mono-center, Cohort Study to Evaluate the Short- and Long-term Effects of 0.5mg Intraocular Ranibizumab (Lucentis) Injections on Retinal Function in Patients With Wet Age-related Macular Degeneration During Twelve Month

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: University of Luebeck · Academic / Other
• Sex: All
• Age: 50 Years
• Healthy volunteers: Not accepted

Summary

Multifocal-electroretinoram (ERG) and microperimetry are objective criteria to asses retinal function. No information besides visual acuity exist for the development of retinal function during the course of wet AMD during therapy with Lucentis. The aim of our study is to evaluate the value of multifocal-ERG and microperimetry as an sensitive tool and early predictor of recurrence of the disease. The second goal will be to evaluate the neuroprotective effects of an adequate therapy on retinal function using microperimetry and multifocal-ERG during the course of wet AMD.

Conditions

• Age-Related Macular Degeneration
• Retinal Function

Interventions

Type	Name	Description
DRUG	Lucentis (Ranibizumab)	Ranibizumab Short- and Log-term Effects on Retinal Function measured by Multifocal-ERG and Microperimetry

Timeline

• Start date: 2010-10-01
• Primary completion: 2013-03-01
• Completion: 2014-04-01
• First posted: 2011-01-04
• Last updated: 2015-04-08

Locations

1 site across 1 country: Germany