NCT01265420

Efficacy and Safety of Xiaflex Injection for Treatment of Dupuytren's Contracture of the Thumb

The Efficacy and Safety of Xiaflex Injections for the Treatment of Thumb Cords in Dupuytren's Contractures

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 7 (actual)
• Sponsor: Indiana Hand to Shoulder Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This study will evaluate the efficacy and safety of clostridial collagenase injections for treatment of Dupuytren's contracture of the thumb and first web space. The investigators hypothesis is that clostridial collagenase will have safety not significantly different to that demonstrated in Phase III clinical trials, and will be effective in significantly reducing the degree of thumb contracture.

Conditions

• Dupuytren's Contracture

Interventions

Type	Name	Description
BIOLOGICAL	Injectable clostridial collagenase	Injection of 0.58mg clostridial collagenase into Dupuytren's cord, up to three injections

Timeline

• Start date: 2010-12-01
• Primary completion: 2014-02-01
• Completion: 2014-02-01
• First posted: 2010-12-23
• Last updated: 2015-04-30
• Results posted: 2015-04-09

Locations

1 site across 1 country: United States