NCT01264848

Endovascular Treatment for Chronic Cerebrospinal Venous Insufficiency (CCSVI)

Endovascular Correction of Chronic Cerebrospinal Venous Insufficiency (CCSVI) and Evaluation of Influence of These Treatments on the Symptoms of Multiple Sclerosis

• Status: Completed
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: Euromedic Specialist Clinics, Poland · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

The aim of this study is to assess the efficacy of endovascular treatment (balloon angioplasty and/or stenting) for the improvement of clinical symptoms in multiple sclerosis patients.

Detailed description

The aim of this study is to assess the efficacy of endovascular treatment (balloon angioplasty and/or stenting) for the improvement of clinical symptoms in multiple sclerosis patients measured by Extended Disability Severity Score (EDSS), Multiple Sclerosis Impact Scale-29 (MSIS-29), Fatigue Severity Scale (FSS) and heat intolerance

Conditions

• Multiple Sclerosis

Interventions

Type	Name	Description
PROCEDURE	balloon angioplasty and/or stenting	balloon angioplasty and/or stenting of internal jugular veins and/or azygous vein and/or brachiocephalic veins
PROCEDURE	balloon angioplasty and/or stenting	balloon angioplasty and/or stenting of extracranial vein draining the central nervous system, on condition that such outflow pathology has been confirmed using catheter venography

Timeline

• Start date: 2010-03-01
• Primary completion: 2010-10-01
• Completion: 2012-12-01
• First posted: 2010-12-22
• Last updated: 2015-02-10

Locations

1 site across 1 country: Poland