NCT01264003

Antibiotic Prophylaxis in Mesh Repair of Inguinal Hernias

Single Dose Antibiotic Prophylaxis in Lihtenstein Repair for Primary Inguinal Hernias

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 200 (actual)
• Sponsor: Diskapi Teaching and Research Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Inguinal hernia repairs is clean surgical procedures. However infection may be a concern when prosthetic materials are used. This prospective randomized study has been set to observe if antibiotic prohylaxis is of benefit in mesh repair of inguinal hernias.

Detailed description

There are two group in the study. Control group received no antibiotic prohylaxis, whereas a single dose 1 gr. intravenous cefazoline is given to the patient in prophylaxis arm of the study. 30-days surgical site infection rates and 1 year prosthetic intervention late infection rates are observed and recorded. Side effects of antibiotic used are also recorded.

Conditions

• Inguinal Hernia

Interventions

Type	Name	Description
DRUG	sefazolin	In prophylaxis

Timeline

• Start date: 2008-05-01
• Primary completion: 2010-12-01
• Completion: 2010-12-01
• First posted: 2010-12-21
• Last updated: 2010-12-21