NCT01262729

Xenon and Therapeutical Hypothermia After Successful Cardiopulmonary Resuscitation

• Status: Terminated
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 5 (actual)
• Sponsor: RWTH Aachen University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

In this clinical trial will be checked, whether 2 hour ventilation with xenon has neuroprotective effects in patients with out of hospital cardiac arrest and successful cardiopulmonary resuscitation

Detailed description

Patients with out of hospital cardiac arrest and successful cardiopulmonary resuscitation will be randomized in two groups. First group (Treatment group) will be inhalated with xenon within 2 hours in addition to therapeutical hypothermia. The second group (Control group) will be treated with therapeutical hypothermia in accordance to international guidelines.

Conditions

• Efficacy and Safety of Xenon Inhalation
• Successful Cardiopulmonary Resuscitation
• Addition to Therapeutical Hypothermia

Interventions

Type	Name	Description
PROCEDURE	therapeutical hypothermia	Patients after successful cardiopulmonary resuscitation will be treated in accordance to international guidelines (Guidelines 2005 on cardiopulmonary resuscitation. Resuscitation 2005; 67: S7-S23)
DRUG	Xenon Inhalation	Patients after successful cardiopulmonary resuscitation will be inhalated with 65-70% Xenon within 2 hours additional to therapeutical hypothermia

Timeline

• Start date: 2011-09-01
• Primary completion: 2014-11-01
• Completion: 2014-12-01
• First posted: 2010-12-17
• Last updated: 2015-09-23

Locations

1 site across 1 country: Germany