NCT01259076

Effect of Weight Loss on Breast Density Using Digital Mammography and MRI in Women Who Are At Increased Risk For Breast Cancer

Effect of Weight Loss on Breast Density Using Both Digital Mammography and Breast MRI

• Status: Terminated
• Phase: —
• Study type: Observational
• Enrollment: 43 (actual)
• Sponsor: Northwestern University · Academic / Other
• Sex: Female
• Age: 30 Years – 50 Years
• Healthy volunteers: Accepted

Summary

Diagnostic procedures, such as digital mammography and MRI, may help measure how weight loss affects breast density in women who are at increased risk for breast cancer.

Detailed description

OBJECTIVES: I. To determine if weight loss in patients undergoing Roux en Y gastric bypass procedures has any effect on breast density as measured by mammography and breast MRI. OUTLINE: GROUP I: Participants undergo mammography and MRI at baseline and 1 year. Participants also undergo gastric bypass surgery. GROUP II: Participants undergo mammography and MRI at baseline and 1 year. After completion of study treatment, patients are followed up at 1 year.

Conditions

• Healthy, no Evidence of Disease

Interventions

Type	Name	Description
PROCEDURE	magnetic resonance imaging	Undergo MRI at baseline and 1 year later.
PROCEDURE	digital mammography	Undergo digital mammography at baseline and 1 year later.
PROCEDURE	conventional surgery	Undergo gastric bypass surgery

Timeline

• Start date: 2011-02-01
• Primary completion: 2014-07-01
• Completion: 2014-07-01
• First posted: 2010-12-13
• Last updated: 2015-04-10

Locations

1 site across 1 country: United States