Clinical Trials Directory

Trials / Completed

CompletedNCT01257425

Equivalence of Intramuscular (IM) Versus Subcutaneous (SC) Applications of Long Acting Pamorelin 11.25 mg

A Phase II, Multicentre, Open, Prospective, Randomised, Parallel-Group, Pharmacodynamic Equivalence Study on Intramuscular Versus Subcutaneous Applications of Triptorelin Pamoate (Pamorelin® LA 11.25 mg) in Patients With Advanced Prostate Cancer

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
109 (actual)
Sponsor
Ipsen · Industry
Sex
Male
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to demonstrate the pharmacodynamic equivalence of triptorelin pamoate (Pamorelin® LA 11.25 mg), applied either IM or SC, in terms of the area under the curve \[AUC1-85day\] for serum testosterone in patients with advanced prostate cancer.

Conditions

Interventions

TypeNameDescription
DRUGTriptorelin Pamoate (Pamorelin® LA 11.25 mg)Pamorelin® LA 11.25 mg administered as standard IM injection (= reference group) at Day 1 and Day 85. Triptorelin Pamoate (Pamorelin® LA 11.25 mg) applied subcutaneously (s.c.) at Day 1 and Day 85.

Timeline

Start date
2010-12-01
Primary completion
2012-02-01
Completion
2012-05-01
First posted
2010-12-09
Last updated
2019-02-08
Results posted
2014-05-26

Locations

22 sites across 1 country: Germany

Source: ClinicalTrials.gov record NCT01257425. Inclusion in this directory is not an endorsement.