NCT01251679

Household Influenza Transmission Study

Study to Assess Effectiveness of Nonpharmaceutical Interventions (Handwashing, Face Mask Use) to Prevent Influenza Transmission in Households

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 2,920 (actual)
• Sponsor: Centers for Disease Control and Prevention · Federal
• Sex: All
• Age: 1 Month – 15 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether nonpharmaceutical interventions (i.e., handwashing and masks) reduce secondary transmission of influenza in households.

Detailed description

HITS is a multi-year project that will prospectively identify laboratory-confirmed influenza infected children. Secondary influenza infection will then be examined among members of the child's household and effectiveness of non-pharmaceutical interventions to decrease secondary infection will be assessed. The pediatric influenza-infected index case will be identified by rapid influenza testing and their household will then be enrolled and randomized to one of three study arms: control, hand washing (Intervention 1), and hand washing and mask use (Intervention 2). Following enrollment, at days 0, 3 and 7, all household participants will be tested: the index case will be assessed for influenza viral shedding and household members will be assessed for secondary influenza infection. This study is being conducted at Queen Sirikit Institute for Child Health in Bangkok.

Conditions

• Influenza

Interventions

Type	Name	Description
BEHAVIORAL	Hand washing	hand washing education and material
DEVICE	Hand washing and surgical mask	hand washing education and material and paper surgical face masks

Timeline

• Start date: 2008-04-09
• Primary completion: 2012-11-12
• Completion: 2013-11-01
• First posted: 2010-12-02
• Last updated: 2024-09-19

Locations

1 site across 1 country: Thailand