Trials / Completed
CompletedNCT01251510
Bile Acid-induced GLP-secretion. A Study in Cholecystectomized Subjects
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 20 (actual)
- Sponsor
- University Hospital, Gentofte, Copenhagen · Academic / Other
- Sex
- All
- Age
- 18 Years – 70 Years
- Healthy volunteers
- Accepted
Summary
PURPOSE The goal of the present project is to unravel the importance of bile acid-induced GLP-1 secretion (via the G protein-coupled receptor TGR5) in human physiology. In the present study the investigators examine the GLP-1 secretion in healthy subjects and cholecystectomised patients. Thereby the investigators aim to show, that cholecystectomised patients have reduced bileflow after a meal, and as a consequence exhibit a diminished GLP-1 response as compared to healthy subjects.
Conditions
Timeline
- Start date
- 2010-10-01
- Primary completion
- 2011-06-01
- Completion
- 2011-06-01
- First posted
- 2010-12-02
- Last updated
- 2013-01-23
Locations
1 site across 1 country: Denmark
Source: ClinicalTrials.gov record NCT01251510. Inclusion in this directory is not an endorsement.