NCT01251081

Effect of the Intensity of Continuous Renal Replacement Therapy

Effect of the Intensity of Continuous Renal Replacement Therapy in Patients With Sepsis and Acute Kidney Injury: Single-center Randomized Clinical Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 280 (actual)
• Sponsor: Zhejiang University · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

In patients with sepsis and AKI, increasing the intensity of renal replacement therapy from 50 mL/kg/h (HVHF) to 85 mL/kg/h (EHVHF)will increase the survival at 28 days and 90 days.

Conditions

• Optimal Intensity of Renal Replacement Therapy on Sepsis Patients

Interventions

Type	Name	Description
OTHER	extra high volume hemofiltration	extra high volume hemofiltration (85 mL/kg/h, EHVHF)
OTHER	high volume hemofiltration	high volume hemofiltration (50 mL/kg/h, HVHF)

Timeline

• Start date: 2004-01-01
• Primary completion: 2009-08-01
• Completion: 2010-06-01
• First posted: 2010-12-01
• Last updated: 2010-12-01

Locations

1 site across 1 country: China