Trials / Completed
CompletedNCT01250405
Acute Effects of Cinacalcet on Arterial Stiffness and Ventricular Function in Hemodialysis Patients
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 23 (actual)
- Sponsor
- Laval University · Academic / Other
- Sex
- All
- Age
- 18 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
The primary objective is to determine whether reduction of serum calcium concentration by cinacalcet leads to reduction of mean blood pressure adjusted c-fPWV. The secondary objectives are to study the effects of calcium reduction on 1) carotid-radial PWV (c-rPWV), 2) common carotid artery (CCA) biomechanics, 3) pulse wave profile and cardiac function.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Cinacalcet | One sequence receives Cinacalcet 30mg /d for 7 days followed by placebo for 7 days |
| DRUG | Placebo | One sequence receives placebo for 7 days followed by Cinacalcet 30mg/d for 7 days |
Timeline
- Start date
- 2012-05-01
- Primary completion
- 2014-04-01
- Completion
- 2014-04-01
- First posted
- 2010-11-30
- Last updated
- 2014-04-07
Locations
1 site across 1 country: Canada
Source: ClinicalTrials.gov record NCT01250405. Inclusion in this directory is not an endorsement.