NCT01246726

Multiple Oncological Serial Scans Study

The Tumour Bed as Target for Breast Irradiation Following Breast Conserving Surgery

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 9 (actual)
• Sponsor: University Hospitals Bristol and Weston NHS Foundation Trust · Academic / Other
• Sex: Female
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

This is a pilot study comparing the appearance and volume of the post surgical region in the intact breast, as determined by 3 modalities: computed Xray tomography (CT), 3 Dimensional ultrasound (USS), Magnetic resonance imaging (MRI) after breast conserving surgery and during whole breast irradiation.

Detailed description

Consenting patients who have undergone breast conserving surgery and who are planned to receive radiotherapy will have their first MRI and CT scan within 2 weeks of treatment planning. This will be followed by 3 weeks radiotherapy treatment. 3D ultrasound scans will be performed in the first 2 weeks before radiotherapy, during the 2nd and 3rd weeks of radiotherapy and in the 2 weeks following radiotherapy.Following the radiotherapy patients will undergo both CT and MRI scans within 2 weeks of treatment completion.The whole process should take approximately 10 weeks.In this study the CT scans, MRI scan + USS are above standard care and are the additional interventions in this study group.

Conditions

• Breast Cancer

Interventions

Type	Name	Description
PROCEDURE	CT SCAN	Prior to radiotherapy + after radiotherapy completion
PROCEDURE	MRI scan	Prior to radiotherapy + after completion of radiotherapy
PROCEDURE	3D Ultrasound scan	Prior to radiotherapy + after completion of radiotherapy

Timeline

• Start date: 2010-11-01
• Primary completion: 2013-03-01
• Completion: 2013-03-01
• First posted: 2010-11-23
• Last updated: 2016-11-15

Locations

1 site across 1 country: United Kingdom