Trials / Completed
CompletedNCT01245257
Effects of Prednisolone and Pentoxifylline on the Regulation of Urea Synthesis in Alcoholic Hepatitis
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 50 (estimated)
- Sponsor
- University of Aarhus · Academic / Other
- Sex
- All
- Age
- 18 Years – 70 Years
- Healthy volunteers
- Not accepted
Summary
Loss of total mass of muscles (catabolism) is a serious clinical problem in patients with alcoholic hepatitis. The liver might play an important role in this stress-catabolism by increasing the production of urea during the inflammatory process. The purpose of this study is to examine the regulation of urea synthesis in patients with alcoholic hepatitis and to study the effect of the anti-inflammatory drugs prednisolone and pentoxifylline on this regulation.
Conditions
Timeline
- Start date
- 2010-11-01
- Primary completion
- 2015-06-01
- Completion
- 2015-06-01
- First posted
- 2010-11-22
- Last updated
- 2016-09-12
Locations
1 site across 1 country: Denmark
Source: ClinicalTrials.gov record NCT01245257. Inclusion in this directory is not an endorsement.