Trials / Completed
CompletedNCT01245140
Efficacy of Alitretinoin Treatment in Patients With Pustular Form of Psoriasis
Efficacy of Oral Alitretinoin Treatment in Patients With Palmo-plantar Pustulosis (PPP) Inadequately Responding to Standard Topical Treatment
- Status
- Completed
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 33 (actual)
- Sponsor
- Stiefel, a GSK Company · Industry
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The main purpose of this study is to demonstrate the improvement in the skin condition rate of patients receiving alitretinoin compared to patients receiving placebo.
Detailed description
Palmo-plantar pustulosis (PPP) is an inflammatory skin disease affecting palms and soles. The disease is considered as a sub-form of psoriasis and presents with sterile pustules of the palms and the soles. This study investigates the efficacy of alitretinoin in patients who have not responded to topical drugs (e.g., steroid creams), who are suffering for at least 6 month from the condition and whose disease severity is confirmed by a score.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | alitretinoin | to receive verum (20 patients) |
| DRUG | Placebo | to receive placebo (10 patients) |
Timeline
- Start date
- 2011-04-26
- Primary completion
- 2014-03-12
- Completion
- 2014-04-16
- First posted
- 2010-11-22
- Last updated
- 2017-12-21
- Results posted
- 2017-04-04
Locations
8 sites across 4 countries: France, Germany, Netherlands, United Kingdom
Source: ClinicalTrials.gov record NCT01245140. Inclusion in this directory is not an endorsement.