NCT01245075

Deep Brain Stimulation of the Nucleus Accumbens as a Novel Treatment in Severe Opioid Addiction

• Status: Unknown
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 10 (estimated)
• Sponsor: Jens Kuhn · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The main objective of this study is to assess the efficacy of bilateral deep brain stimulation (DBS) of the Nucleus accumbens (NAc) as a novel treatment in severe opioid addiction. The included patients have been treated so far with a substitute in form of methadone. Our hypothesis is that bilateral DBS of the NAc will significantly reduce the craving for heroin and thus enable the patients to decrease their Levomethadone-dosage substantially.

Conditions

• Addiction

Interventions

Type	Name	Description
OTHER	Deep brain stimulation	Deep brain stimulation on
OTHER	Placebo	deep brain stimulation off

Timeline

• Start date: 2011-01-01
• Primary completion: 2017-06-01
• Completion: 2017-12-01
• First posted: 2010-11-22
• Last updated: 2016-12-07

Locations

1 site across 1 country: Germany