NCT01242644

Comparison of a Pain Pump Versus Injectable Medication for Analgesia in Knee Arthroscopy

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 48 (actual)
• Sponsor: University of South Alabama · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Hypothesis: Ropivacaine, morphine and ketorolac injected after knee arthroscopy is as effective as this solution plus ropivacaine administered intra-articularly for twenty-four hours. Three groups were assigned random patients, each group provided a different method of pain medication in order to determine the effectiveness of each treatment.

Detailed description

Arthroscopic knee patients were randomized to 1 of 3 groups. A) 30mL of ropivacaine (0.5%), 30mg of ketorolac and 8mg of morphine sulfate injected plus a pain pump containing 100mL of ropivacaine (0.5%) administered at 4 mL/hour; B) an identical solution plus a pain pump containing 100-mL of normal saline administered at 4 mL/hour; C) an identical solution and no pain pump. Pain level, the amount of pain medication used and time to discharge were recorded. Clinical and radiographic evaluation was performed at nine months after surgery.

Conditions

• Pain

Interventions

Type	Name	Description
DEVICE	pain pump containing ropivacaine	30mL of ropivacaine (0.5%), 30mg of ketorolac and 8mg of morphine sulfate injected plus a pain pump containing 100mL of ropivacaine (0.5%) administered at 4 mL/hour
DEVICE	saline pain pump with injectable medication	30mL of ropivacaine(0.5%), 30mg of ketorolac and 8mg of morphine sulfate injected plus a pain pump containing 100-mL of normal saline administered at 4 mL/hour
DRUG	ropivacaine, ketorolac , morphine sulfate	30mL of ropivacaine (0.5%), 30mg of ketorolac and 8mg of morphine sulfate injected

Timeline

• Start date: 2006-10-01
• Primary completion: 2009-10-01
• Completion: 2010-06-01
• First posted: 2010-11-17
• Last updated: 2020-11-27
• Results posted: 2020-11-27