NCT01238731

Persistent Pulmonary Artery Hypertension After Valve Replacement

Persistence of Severe Pulmonary Artery Hypertension in Patients After vaLve replacemenT

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 300 (estimated)
• Sponsor: University Hospital, Bonn · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Background: Persistent severe pulmonary hypertension (PH) after mechanical valve replacement is a frequent finding in patients with severe valve-diseases. The reasons to develop PH are multifactorial and the prevalence of severe PH significantly worsens the patients´ outcome. Aims: (i) To define the prevalence of PH in patients after valve replacement and (ii) to identify factors predicting persistent PH. Methods: All patients which underwent valve replacement at our institution between the years 2008 -2010 will be screened retrospectively. Those patients with pre- procedural proven PH by means of right-heart catheterization will receive prospective follow-up with echocardiography. Diagnosis of persistent PH will be confirmed with right heart catheterization.

Conditions

• Persistent Severe PH After Valve Therapy

Timeline

• Start date: 2011-01-01
• Primary completion: 2011-01-01
• Completion: 2012-03-01
• First posted: 2010-11-11
• Last updated: 2010-11-11

Locations

1 site across 1 country: Germany