NCT01237548

The Evaluation of the Acute Effect of Water-Pipe Smoking on the Endothelial Function and the Respiratory System

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 62 (actual)
• Sponsor: Rambam Health Care Campus · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Title: The acute effect of narghile smoking on endothelial Function, and exhaled breath condensate (EBC) and pulmonary function tests in healthy volunteers. Objectives: To evaluate the acute effect of one cession of narghile smoking on endothelial Function, airway inflammation as assessed by exhaled breath condensate (EBC) in healthy volunteers. Design: Prospective study evaluating these parameters before and after 30 minutes of Narghile smoking. The changes in inflammatory parameters pre and post smoking will be evaluated blindly. Sample size: 50 participants Participant selection: Adults subjects who smoke Narghile . Intervention: Each subject will undergo evaluation including a respiratory questionnaire, endothelial Function , pulmonary function tests , exhaled breath condensate (EBC) and carboxy- hemoglobin levels . All measurements will be evaluated before and after one cession of 30 minutes narghile smoking.

Conditions

• Healthy

Interventions

Type	Name	Description
OTHER	Smoking Narghile for 30 min	No Other intervention will be used

Timeline

• Start date: 2011-01-01
• Primary completion: 2012-10-01
• Completion: 2012-12-01
• First posted: 2010-11-09
• Last updated: 2013-06-11

Locations

1 site across 1 country: Israel