NCT01235494

Development of New MRI Pulse Sequences for Probing Lung Function in Volunteers With Hyperpolarised 3He Gas

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 36 (actual)
• Sponsor: Sheffield Teaching Hospitals NHS Foundation Trust · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Accepted

Summary

To develop techniques with MRI of Helium-3 gas to give functional images of the lungs. The goal is to test a single breath-hold functional 3-He MRI pulse sequence with sensitivity to multiple functional aspects of the luncg physiology. A group of 20 healthy volunteers willbe recruited from the local research group and the results compared with existing methods that require seperate breath-holds of 3He gas

Conditions

• Healthy Volunteers

Interventions

Type	Name	Description
OTHER	polarised 3 helium	1 inhalation (= 1 litre)

Timeline

• Start date: 2010-07-01
• Primary completion: 2020-12-31
• Completion: 2020-12-31
• First posted: 2010-11-05
• Last updated: 2021-12-29

Locations

1 site across 1 country: United Kingdom